Glutathione and other thiols in biological samples can interfere with the assay
Class III peroxidases are located in extracellular space and are able to produce ROS in plants under certain conditions 7,32,33
Metal-based nanozymes can, depending on their composition, structure and reaction conditions, mediate either ROS clearance (e.g., anti-inflammatory and antioxidative effects) or ROS generation (e.g., tumor catalytic therapy and antibacterial action) by simulating the activities of multiple enzymes, including superoxide dismutase (SOD), catalase (CAT), POD, and glutathione peroxidase (GPx), thereby contributing to the precise regulation of the PME [17,18]
Neurology 2017;88:16421649