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Additionally, macrophages in chronic wounds often fail to switch from a pro-inflammatory phenotype to a pro-healing phenotype, resulting in a feed-forward loop of inflammation that prevents resolution

Fujii S, Magliocco AM, Valtorta E, Kim J, Okamoto W, Kim JE, Sawada K, Nakamura Y, Torri V, Kopetz S , Park WY, Tsuchihara K, Kim TW, Raghav KPS, Siena S, Yoshino T

Its ability to modulate key signaling pathways and reduce inflammatory cytokines highlights its potential in treating muscle wasting phenotypes 7

Collectively, our study demonstrates GSNO as a potential therapeutic agent for the treatment of intraocular infections due to its dual anti-inflammatory and cytoprotective properties