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doi: 10.3816/cgc.2003.n.023

Mechanism of Action 5-Amino-1MQ acts as a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue, liver, and certain metabolically active cells

Aptamers as targeted therapeutics: current potential and challenges

Mechanism literature Multiple peer-reviewed papers describe VEGFR2 activation, eNOS/NO signaling, and tendon-cell behavior in cultured cells and rodent models (Chang et al., Journal of Applied Physiology, 2011