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Representative domains include: Gastrointestinal and hepatic models: Protection against ulcers, leaky gut, IBSlike symptoms, Crohntype inflammation, and toxic liver injury (e.g., CCl4, NSAID, and alcohol models), with improved mucosal healing and barrier integrity

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Although these factors are considered to be the major controls, regulation is possible at other levels, such as the availability of glycine and ATP (Buwalda et al., 1990

A number of studies have demonstrated a close association between PD-related genes and mitochondrial integrity