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Such pleiotropic effects agree with BPC 157 functioning through activation of several receptors (i.e., Vegfr2 (Hsieh et al., 2017), growth hormone (Chang et al., 2014)), and interaction with several molecular pathways (Chang et al., 2011, 2014

Because the BPC-157 peptide operates through VEGFR2 and NO pathways that are mechanistically distinct from TB-500s actin-based signaling and GHK-Cus collagen synthesis mechanisms, the three compounds address complementary aspects of tissue repair without documented antagonism in animal studies

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