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Adverse events that may occur with anti-TNF therapy include formation of antibodies against the therapy, infusion or injection site reactions, delayed hypersensitivity reactions, autoantibody formation, drug-induced lupus, infection (particularly tuberculosis and fungal infections such as histoplasmosis), psoriasis, and possibly lymphoma and skin cancers

R Many chronically ill individuals are functionally glycine-deficient because demand exceeds endogenous synthesis and dietary intake

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