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Prolonged AF-mimicking (irregular) pacing (7 days) of human induced pluripotent stem-cell derived cardiomyocytes (hIPSC-CMs) reduced the Ca 2+ -transient and SR Ca 2+ -stores, while oxidizing CaMKII at Met282/282 (which activates CaMKII) and reducing SERCA2a function compared to regular pacing at the same rate (60 bpm)
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Most viral illnesses will take 45 days before getting better and up to 3 weeks for a full recovery
