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In fact, the reactive species interactome has been the subject of a very interesting review stating that the adaptive, selective and evolutionary cellular mechanisms that are required to overcome oxidative stress are largely dependent on cysteine redox switches, leading to enzyme modification and improved antioxidant capacity

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The sensitivity of R 4 parameters ( k p4 ) with respect to model OCR output is in good accordance with the AIC/BIC analysis, confirming the need for the R 4 reaction, which is present in both the triad and the comproportionation models, but not in the reduced model

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