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Clinical Insight Shifting from population averages to multi-omic, N-of-1 carewhile actively modulating the autonomic nervous systemallows physicians to directly influence and verify changes in key inflammatory and vascular pathways (e.g., NLRP3, nitric oxide biology), improving precision and efficiency of interventions

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2009 May 8;1216(19):4245-51

FIGURE 5 5.1 Alzheimers disease Alzheimers disease is a common neurodegenerative disease with clinical symptoms including cortical degeneration with severe memory loss, cognitive impairment, and behavioral abnormalities