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This was also confirmed by Gross et al., who indicated that migraine can, in some part, be related to energy deficits in the brain and the experienced pain stems from brain hypometabolism and oxidative stress triggered by the factors commonly causing headache (e.g., fasting, physical exertion, excess sleep or sleep deprivation, intense aromas, or photosensitivity) due to their direct or indirect effect on energy metabolism and mitochondrial activity [22]
Control of EGF receptor signaling by clathrin-mediated endocytosis
(0.03 MB DOC) Figure S7
Glycine, though technically classified as a non-essential amino acid, becomes conditionally essential when the body is under high oxidative demand, as the endogenous synthesis cannot keep up with the rapid consumption
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