glutathione redox cycle synthesis and its role in signaling Reduced and Oxidised Glutathione —

168 Cadmium exposure leads to gut flora dysbiosis, reduced fecal BSH activity, and elevated intestinal tauro--muricholic acid levels in mice, subsequently inhibiting the intestinal FXR/FGF-15 signaling pathway, promoting hepatic bile acid synthesis, and ultimately triggering bile duct proliferation, inflammation, and injury

That is speculative pending trial data

Toxicol Appl Pharmacol 204:329342 Sun X, Shih AY, Johannssen HC, Erb H, Li P, Murphy TH (2006) Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface

Parasitol Res (2012) 111(5):18717