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Though less common than other alternatives, gum or candy cigarettes might be used for comedic effect or in scenes where a cigarette is needed as a prop but does not need to be smoked

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Anti-HCC by restoring p53 function and normalizing MDM2p53 interaction Until now, there are some strategies that have been considered in p53 reactivation 140 , including disrupting the MDM2p53 interaction, releasing p53 by small molecules, restoring wild-type function to mutant p53 by covalent modification of its core domain, and reconstructing a functional copy of p53 by viral or nonviral DNA transfection