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What started as a bottom-up community of micro-manufacturers and early adopter vapers (as distinct from smokers) by around 2007 began to attract the interest of Big Tobacco who embarked on a programme of developing their own products and taking over some of the original starts-up

"Electronic cigarettes are not a healthy habit but they are a safer alternative to tobacco cigarettes," Dr Konstantinos Farsalinos from the Onassis Cardiac Surgery Center in Athens told the annual meeting of the European Society of Cardiology

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As I reported at the time, Hestia applied under the substantial equivalence pathway, which was supposed to be the easy path to FDA authorization