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Nicotinic receptors modulate neurotransmission in a broad range of neuronal pathways

This potent, nearly instantaneous cigarette high is profoundly different from the experience of cigar and pipe smokers who absorb nicotine through their mouth, not the lungs

Heres the theory to these alternatives: If a nicotine-containing product doesnt burn tobaccoand therefore doesnt generate smokeit should produce lower levels of harmful chemicals than a cigarette, and that should lead to reduced effects on the body compared with cigarettes

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