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(2009) Sensitization to wheat flour and enzymes and associated respiratory symptoms in British bakers

While the focus of this section is on DNA methylation and hydroxymethylation in relation to oxidative stress, smoking, and cancer, we refer the readers to elegant and comprehensive reviews on other epigenetic mechanisms, such as histone modifications and variants, miRNA deregulation, chromatin remodeling, and nucleosome positioning [221, 223, 224, 264, 265], which fall outside the scope and space limit of this review article

What this means for your own plan If your goal is a similar outcome, the method is chosen after the design

Its likely people with vasomotor rhinitis have heightened sensitivity to various substances and environmental changes that would trigger a response in most people just in higher amounts