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Wise JP, Young JL, Cai J, Cai L (2022) Current understanding of hexavalent chromium neurotoxicity and new perspectives

In 1974, after forcing polonium into the tracheas of hamsters, Little and fellow Harvard scientist William OToole were able to confirm that hypothesis: 94 percent of hamsters in the highest-exposure group developed lung tumors with doses so small that their tissues showed no inflammation

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The FDA chose nine images from the first proposed 36 after reviewing the related scientific literature, analyzing the results from an 18,000-person study and taking into account more than 1,700 comments from many groups, including the tobacco industry, retailers, health professionals, public health and other advocacy groups, academics, state and local public health agencies, medical organizations and individual consumers