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7.2 The mechanism and molecular target of taurine The main mechanism for the absorption of taurine in tissues is through the chloride sodium taurine transporter, and it has been found that Gamma-aminobutyric acid (GABA) transporter 2 at BBB is capable of transporting hypotaurine and taurine (127)

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This leads to peripheral and hepatic insulin resistance and compensatory intra-portal hyperinsulinemia, which results in increased hepatic GH sensitivity that aggravates the condition further ( Table 1