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In antioxidation mechanism, plant metabolites (flavonoids, terpenoids, tannins, polyphenols, vitamins A, C, E, and minerals such as selenium) prevent, stop or reduce oxidative damage due to phospholipase A 2 activity by selectively binding to the active sites or modifying the conserved residues that are inevitable for phospholipase A 2 catalytic action [119]

The FDA says nicotine products are highly addictive and are not risk-free even for adults, while nicotine can harm developing brains

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The most effective addiction treatment program for them will depend on their individual needs and circumstances