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This commonly includes lifelong treatment for pernicious anaemia, managing severe B12 deficiency with neurological symptoms to prevent further damage, and for individuals post-gastric surgery due to impaired absorption

Problems arise when nitric oxide production decreases or when the molecule gets broken down too quickly

One bottle offers 60 capsules at 250 mcg per capsule

Nevertheless, preliminary studies that find the right non-toxic dosage is important, whether in vitro or in vivo as screening for study feasibility, but still, further human study is required to determine the dose safety and efficacy (Stohs and Hartman, 2015)