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However, there has been little discussion about the relationship between smoking-induced oxidative stress and pyroptosis

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therefore, the intensity of erythema cannot be used to differentiate between them.6 With respect to this characteristic, other authors report that the distribution of the erythema is more important than its intensity, with nonallergic reactions defined as those without diffuse erythema, even if they involve isolated perifollicular erythema and follicular crusts are present.8 Therefore, they describe the dermoscopic characteristics of irritant reactions as pore reaction and/or perifollicular reaction, in the absence of homogeneous basal erythema