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The peptide accelerates healing across a range of wound types, including surgical incisions, chronic ulcers, and traumatic injuries, with time reductions of 30-50% reported in multiple studies

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision