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Discovery and Pharmacological characterization of JNJ-42756493 (Erdafitinib), a functionally selective small-molecule FGFR family inhibitor

The evidence base, such as it is, differs meaningfully across clinical targets, and it is worth examining each major application area on its own terms

Neuron 72 , 231243 (2011)

This totally subjective study that lacked the necessary control group(s) concluded that, in 14 of the patients, intraarticular injection of BPC-157 helps with multiple types of knee pain. In a similar 2014 study that also lacked any controls, the same group reported that BPC 157 was effective in relieving the pain associated with interstitial cystitis (bladder pain) in 10 of 12 women