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In the treatment of inflammatory diseases such as RA, the combination of ART and DEX not only plays a role by inhibiting the HIF-1/NF-B signaling pathway, but also promotes ROS scavenging and macrophage polarization from M1 to M2, which modulates inflammatory responses at multiple levels, providing a new perspective for antioxidant treatment strategies (75)

The predominant bacterial phyla identified in gallstone bile through metaproteomic analysis were Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes, displaying similarities to the composition revealed by 16S rRNA sequencing, albeit with differences in taxonomic order (Molinero et al., 2019)

This was done by employing an engineered cyst(e)inase enzyme resulting in the suppression of tumor growth in breast and prostate cancer xenografts (53)