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Query: Based on duplex imaging, does the patient have DVT involving (a) right lower extremity only, (b) left lower extremity only, or (c) both lower extremities (bilateral DVT)? Treatments (Clinical) Evidence-based DVT management follows guidelines from the American Society of Hematology (ASH) 2020 VTE Guidelines and the American College of Chest Physicians (ACCP) CHEST Guidelines: Anticoagulation First-Line Treatment DOACs (preferred for most patients): Apixaban 10 mg BID 7 days 5 mg BID