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NNMT is upregulated in the white adipose tissue of obese animals and humans, and its activity is mechanistically linked to depleted cellular NAD+ and SAM pools

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Product access for 5 AMINO 1MQ liquid in the Umbrella Labs catalog is available here: 5 AMINO 1MQ is widely discussed in the scientific literature as a tool compound used to interrogate nicotinamide N methyltransferase, commonly abbreviated as NNMT, a cytosolic enzyme that transfers a methyl group from S adenosyl L methionine to nicotinamide, yielding 1 methylnicotinamide

It enters circulation and activates the same gene expression cascades throughout the body affecting collagen synthesis in skin, wound healing in connective tissue, and potentially neuroprotection in the nervous system