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Our data suggest that choline can promote liver health by maintaining cholesterol homeostasis.10 Choline induces glucose and insulin intolerance in Pemt(-/-) mice through modulating plasma glucagon and its action in liver.11 Choline supplementation decreased the concentration of liver triacylglycerol during the first 4 wk after parturition

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This differential regulation allows therapeutic benefits without common side effects associated with NO manipulation