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GSH and zinc have a complicated relationship that affects genomic integrity through direct antioxidant actions, DNA repair mechanism regulation, and gene expression modulation [75]

These insights advance our mechanistic understanding of ferroptosis and illuminate its potential connections to neurodegenerative pathologies

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Liu W, Chen B, Wang Y, Meng C, Huang H, Huang XR et al (2018) RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism