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Ethics statement The animal study was approved by the Ethics Committee of Shanghai General Hospital Affiliated with Shanghai Jiaotong University School of Medicine (IACUC No

FPLC analysis revealed that plasma LDL-C in the HCD + ALC group exhibited a decreasing trend, whereas HDL-C showed an increasing trend (Figure 2D)

Cells were required to have the number of peaks detected between 2,300 and 40,000, the percentage of fragments in peaks greater than 25%, the ratio of the reads that map to the blacklist regions in genome less than 5%, the nucleosome signal 3

An 8mg dose only requires 80 units, which fits easily in a single syringe