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Standard capsules and tablets are often broken down by stomach acid and digestive enzymes before they can be absorbed

NADPH oxidase 4 (NOX4), a ROS-producing enzyme, is highly expressed in the livers of NASH patients and contributes to pathological inflammation and fibrosis in a mouse model of diet-induced NASH (94)

thus, individuals with moderate hypertension (diastolic pressure 105 to 114 mmHg) had about a 50% greater response than patients with mild hypertension (diastolic pressure 90 to 104 mmHg)

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