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We then tested whether other agents that specifically caused nucleotide imbalance (rather than the DNA-driven and RNA-driven effects of 5FU) have the same mechanism of action

The organism, Borrelia burgdorferi , is a master of evasion, utilizing pleomorphism (shape-shifting), biofilm formation, and antigenic variation to survive host defenses and antimicrobial therapies [3]

Segerdahl, A

These compounds directly regulate key signaling pathwayssuch as Wnt/-catenin, BMP/Smad, PI3K/Akt, MAPK, and RANKL/NF-Bto promote osteogenesis and suppress osteoclastogenesis