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This research was supported by grants from the National Natural Science Foundation of China (32388101 and 32250001 to D.X., 32425011 and 32488302 to J.Y.), National Key R&D Program of China (2022YFD1400800 and 2021YFA1300400 to D.X.), China Postdoctoral Science Foundation (2020M670286 to Y.Y.), Postdoctoral Fellowship of Tsinghua-Peking Joint Center for Life Sciences

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The U.S Food and Drug Administration drug labels for GLP-1 receptor agonists include a warning that acute pancreatitis has been observed in patients and that treatment should be discontinued promptly if acute pancreatitis is suspected