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Analyzing the expression levels of acyl-CoA synthetase long chain family member 4, which promotes ferroptosis by upregulating intracellular lipids, can predict the response to neoadjuvant chemotherapy (10)

Unfortunately, as further results of studies indicate, increased activity of antioxidant enzymes was not enough to counterbalance ROS, since significantly higher concentrations of thiobarbituric reactive substances (TBARS, products of lipid peroxidation) and carbonyl groups (products of protein oxidation) were observed vs