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Peptides are short chains of 250 amino acids linked by peptide bonds, while proteins are larger polypeptide chains that typically exceed 50 amino acids and adopt complex three-dimensional structures

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46 GERD presents with a broad spectrum of symptoms that are typically classified into two categories: typical symptoms (such as heartburn, regurgitation, and non-cardiac chest pain) and atypical or extra-esophageal symptoms (Figure 1)