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(PubMed) Potter K, Hankey GJ, Green DJ, Eikelboom J, Jamrozik K, Arnolda LF

Resistance It is known from a disease called diabetes mellitus, that there can be resistance to the actions of the hormone insulin the main regulator of blood glucose concentrations in many individuals

As I elaborate on in my video The Symptoms of Vitamin B12 Deficiency , these include: Abdominal distention Chronic diarrhea Shortness of breath Swollen, red, painful feet Skin darkening Bilateral useless hand syndrome Numbness and tingling in the hands and feet Muscle cramps Dizziness Cognitive disturbances Difficulty walking Erectile dysfunction Fatigue Depression Psychosis Coma Blindness Vitamin B12 Deficiency Treatment Is A Vitamin B12 Shot Better Than Taking B12 Orally

Placebo effects, expectation bias, and individual variability all confound interpretation