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About Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) The Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) is an investigator-initiated study conducted as a multicenter, placebo-controlled, double-blind, randomized Phase III clinical trial to verify the efficacy and safety of high-dose methylcobalamin (mecobalamin) in patients with amyotrophic lateral sclerosis (ALS)

The broad spectrum of its therapeutic applications highlights the need for continued research and clinical trials to fully understand and harness its potential

These data suggest a benign safety profile in animal models

A lack of this important nutrient can cause tiredness, brain changes, and big red blood cells