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The comorbidity spectrum encompasses epilepsy, anxiety, sensory abnormalities, and other multisystem disorders, necessitating comprehensive strategies targeting GABA receptors, ion channel regulation, and the gut-brain axis (100)

This process engages a coordinated network of regulated cell death that extends beyond ferroptosis to include crosstalk with necroptosis and pyroptosis, while being critically modulated by ferritinophagy and the paradoxical role of defective mitophagy

(MoSAEL), Department of Plant Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan

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