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Privalov revealed in 1983 that intrinsically disordered histones H1 and H5 (defined by these authors as denatured random coil proteins) can partially fold in the presence of salt, with folding taking place within their N-terminal 80-residue-long fragments that can be derived from both proteins by trypsin digestion in high salt (Crane-Robinson and Privalov, 1983)

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Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells

[8] The 2023 Menopause Society position statement on hormone therapy states: "For women aged younger than 60 years or within 10 years of menopause onset, the benefits of hormone therapy outweigh the risks for the treatment of bothersome vasomotor symptoms." [8] Midi Health's protocols are explicitly built around this guidance