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Thats why healthcare professionals warn against mixing alcoholic beverages with cold medications, such as DayQuil

doi: 10.1210/jc.2003-030630

Chemico-Biol Interact 231:98107 Natarajan K, Abraham P, Kota R, Isaac B (2018) NF-B-iNOS-COX2-TNF inflammatory signaling pathway plays an important role in methotrexate induced small intestinal injury in rats