glutathione role in mycotoxin detoxification

glutathione role in mycotoxin detoxification of Mycotoxin Contamination: Occurrence, Biotransformation, Pathogenic

Name: glutathione role in mycotoxin detoxification of Mycotoxin Contamination: Occurrence, Biotransformation, Pathogenic
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MacFie J, Reddy BS, Gatt M, et al

glutathione role in mycotoxin detoxification of Mycotoxin Contamination: Occurrence, Biotransformation, Pathogenic

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Inhibition of CYP51A1 with ketoconazole has demonstrated diverse biological effects: it rescued EGFR degradation in A431 carcinoma cells by blocking sterol metabolism upstream of MSMO1, and reduced inflammatory signaling and cytokine release in mouse macrophages, ultimately improving survival in a model of endotoxic shock