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Regeneration also becomes slow due to high cortisol when you do not get enough sleep

doi: 10.1016/j.cell.2018.02.048 66 DuJWangTLiYZhouYWangXYuXet al

Changes in the Intracellular Signaling Cascades It is becoming increasingly evident that current mood-stabilizing agents have actions that extend beyond binding to neuronal membrane surface receptors