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Nutrient Deficiencies Your body needs specific nutrients to metabolize histamine: Vitamin C acts as a natural antihistamine and supports DAO function Vitamin B6 is required for DAO synthesis and histamine breakdown Magnesium stabilizes mast cells and reduces degranulation Zinc modulates immune function and mast cell activity Ironically, copper deficiency can worsen mast cell reactions, even when injecting the copper peptide GHK-Cu

Glutathione acts as a primary defender against oxidative stress

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doi:10.1054/plef.2002.0439 Chauhan A, Chauhan V, Brown WT et al (2004) Oxidative stress in autism: Increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferring-the antioxidant proteins