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[4,5] Method: This is a prospective study with ongoing enrolment of subjects with PD and age and sex matched healthy controls (HC)

Additionally, Oga heterozygous ( Oga +/ ) mice, which exhibit chronically elevated levels of O-GlcNAcylation, display antidepressant-like behaviors, and altered synaptic transmission in the medial prefrontal cortex (mPFC) [46]

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This research emphasizes that the endothelium acts as a permeable barrier between two components, the blood bloodstream and vascular wall maintain the tone of the vesicles