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Preliminary studies show that organic compounds (such as nicotine, pesticide residues and metal) seep from cigarette butts into aquatic ecosystems , becoming acutely toxic to fish and microorganisms

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Green Tobacco Sickness occurs when workers absorb nicotine through their skin while having prolonged contact with tobacco plants.[57] Researchers have documented dizziness, headaches, nausea, and vomiting as the most common symptoms of acute nicotine poisoning.[58] In some cases, these symptoms may be linked to or exacerbated by pesticide exposure or working in conditions of high heat and high humidity without sufficient rest, shade, and hydration.[59] Acute nicotine poisoning generally lasts between a few hours and a few days,[60] and although it is rarely life-threatening, severe cases may result in dehydration which requires emergency treatment.[61] Children are particularly vulnerable to nicotine poisoning because of their size, and because they are less likely than adults to have developed a tolerance to nicotine.[62] The long-term effects of nicotine absorption through the skin have not been studied,[63] although the long-term effects of consuming tobacco products containing nicotine has been well documented