tobacco causes cancer Cancers linked to use make up 40% of all cancers diagnosed in the United States | CDC Online Newsroom Warning - Tobacco causes mouth

Addict Behav 2003;28:1203-18

[8] Around 2008, hip-hop artists started using RAW and sharing it with their friends

Exposure to CSE from 3R4F, NF and ultralow nicotine cigarettes negatively impacts ZO-1 and occludin expression/distribution as well as BBB integrity Immunofluorescence analysis of BBB endothelial confluent monolayers revealed a significant loss of ZO-1 at cell-cell junctions following exposure to CSE from 3R4F, Ultralow and NF cigarettes and to a lesser extent in 1R5F treated cultures (compared to controls, Figure 4A)

Anyone sensitive to the side effects of traditional tobacco and nicotine but still wanting a convenient, enjoyable experience