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Chronic calorie restriction often leads to metabolic damage, decreased free T3 levels, and increased leptin levels, resulting in weight gain over time

Energy may improve briefly, and that can lead to behavior changes that sometimes subtly change weight, but the vitamin itself is not a fat-burning drug

Experimental findings indicate that the compound may trigger cellular mechanisms that release fatty acids from fat stores without significantly altering insulin or IGF-1 levels

Researchers observed that the peptide stimulates lipolysis in preclinical adipocyte models through a mechanism distinct from full-length growth hormone signaling