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All three were able to be co-cultured with primary hGEC from the same donor as hpPOD inside the GOAC, although hiPOD evidenced a less organized nephrin distribution, lower secretion of matrix proteins, such as collagen IV and laminin, and lower efficiency of permselectivity, which exalts the relevance of shifting away from using cell lines in OoC models

Increased circulating trimethylamine N-oxide plays a contributory role in the development of endothelial dysfunction and hypertension in the RUPP rat model of preeclampsia

Hypertension 67 (3), 606612

When taken orally, these liposomes arrive at the intestinal wall and fuse with the membranes of the cells that line the intestine (see figure 1)