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Our findings describe a role for mitochondrial plasticity as a mechanism for acute 5FU tolerance in CRC cells: mitochondrial changes acutely adopted by CRC cells in response to 5FU-based standard-of-care treatment result in increased mitochondrial biogenesis, which provides metabolic support for increased pyrimidine scavenging by UCK2 to resolve nucleotide stress

Nevertheless, a brief summary of healing properties induced by the compound is presented in Table 1

While most commonly associated with skin rejuvenation, GHK-Cu demonstrates effects on deeper connective tissues

[DOI] [PubMed] [Google Scholar] 41.Kachlik D, Baca V, Stingl J