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Description

Conclusions and perspectives The study of oxidative cell death mechanisms in cancer therapy has revealed promising possibilities for innovative treatment strategies

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IGF-1 LR3 is a modified analogue with an arginine substitution at position 3 and a 13-amino-acid N-terminal extension that reduces binding to IGF-binding proteins and extends half-life in research models

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Five clinical trials met the inclusion criteria

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Interestingly, these markers largely reversed in liver-specific Gclc-Nrf2 DKO mice

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