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It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years

High blood pressure medication You can donate on high-blood pressure medication, as long as your dose has not changed for four weeks

In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)