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Other Off-label Uses: In addition to its approved indications, sertraline may be prescribed off-label for certain conditions where its mechanism of action and pharmacological properties may be beneficial

A related peptide, AHK-Cu (alanine-histidine-lysine copper), is synthetic rather than naturally occurring

Taverna M, Marie AL, Mira JP, Guidet B

Kovalzon and Strekalova, summarizing the field in 2006, were explicit: the link between DSIP and sleep had never been further characterized, in part because of the lack of isolation of the DSIP gene, protein and possible related receptor, and the hypothesis of DSIP as a sleep factor was extremely poorly documented and still weak (Kovalzon & Strekalova, 2006)